Preoperative Immunonutrition in Normonourished Patients Undergoing Fast-track Laparoscopic Colorectal Surgery

University of Rome Tor Vergata

Status: Completed

Conditions: Colorectal Cancer

Treatments: Dietary Supplement: Immunonutrition

Study type: Observational

Funder types: Other

Identifiers

NCT04692545

REGISTROSPERIMENTAZIONI /21

Details and patient eligibility

About

Immunonutrition (IN) appears to reduce infective complications and in-hospital length of stay (LOS) after gastrointestinal surgery. More specifically, it seems to be beneficial also in colorectal cancer surgery. Potential benefits of combining preoperative IN (PIN) with protocols of enhanced recovery after surgery (ERAS) in reducing LOS in laparoscopic surgery are yet to be determined.

Enrollment: 173 patients

Sex: All

Ages: 18+ years old

Volunteers: No Healthy Volunteers

Inclusion criteria

• laparoscopic colorectal resection for cancer following ERAS protocol
• >18 years old
• elective setting

Exclusion criteria

• age below 18
• malnutrition
• inflammatory bowel disease
• acquired or congenital immunodeficiency
• preoperative infection
• ASA IV
• pregnancy
• emergency setting
• conversion to open surgery
• multivisceral resections

Trial design

173 participants in 2 patient groups

A

Description:

patients receiving immunonutrition supply

Treatment:

Dietary Supplement: Immunonutrition

B

Description:

patients receiving standard dietary advice