Preoperative Progression of Macular Holes

Glostrup University Hospital, Copenhagen

Status: Completed

Conditions: Macular Holes

Study type: Observational

Funder types: Other

Identifiers

NCT02203929

MH-Progression

Details and patient eligibility

About

Knowledge of the natural history and progression of macular holes is mainly limited to the studies from the pre-optical coherence tomography era. By observing macular holes preoperatively we are able to determine the extent of the preoperative macular hole progression.

At our institution macular holes are treated in an elective setting. The majority of macular holes undergo a 2-step sequence of phacoemulsification and intraocular lens implantation followed by vitrectomy.

We wish to observe the effect of time and cataract surgery on the progression of macular holes prior to vitrectomy.

Enrollment: 37 patients

Sex: All

Ages: 40 to 120 years old

Volunteers: No Healthy Volunteers

Inclusion criteria

• Idiopathic macular hole stage II-IV
• Informed consent
• Duration of symptoms ≤ 24 months

Exclusion criteria

• Previous vitreomacular surgery
• Ocular trauma
• Significant visual function affecting disease (proliferative diabetic retinopathy, diabetic macular edema, exudative macular degeneration)

Trial design

37 participants in 2 patient groups

Phakic eyes

Description:

Phakic eyes will be monitored with 4 preoperative optical coherence tomography scans as these patients will undergo phacoemulsification and intraocular lens implantation prior to their macular hole surgery

Pseudophakic eyes

Description:

Phakic eyes will be monitored with 2 preoperative optical coherence tomography scans as there is no surgical intervention prior to the macular hole treatment.