Preoperative Strength Training in Patients With Total Knee Arthroplasty

University of Aarhus

Status: Unknown

Conditions: Osteoarthritis, Knee

Treatments: Other: Preoperative strength training

Study type: Interventional

Funder types: Other

Identifiers

NCT01647243

M-20110181

Details and patient eligibility

About

The purpose of this study is to investigate if preoperative strength training will result in faster recovery and higher level of function six weeks after total knee arthroplasty (TKA).

Full description

Reduced strength of the quadriceps muscle is a common clinical finding in patients with Knee Osteoarthritis and this seems to play a central role in the development of the disease. The strength of the quadriceps muscle have been shown to be reduced by 20-40% as compared to age-matched healthy controls and this decrease in muscle strength have been closely associated with a reduced level of function and increase of pain. Furthermore, it has been demonstrated that the preoperative strength of the quadriceps muscle in patients undergoing TKA, is associated with the level of function one year after surgery. Compared to the level before the operation, an additional operation-induced reduction of the strength of the quadriceps muscle up to 60% as has been demonstrated. Presumably, an optimizing of the strength of the quadriceps muscle could counteract the impact of the expected postoperative loss of muscle strength to such an extent that the loss will be of less clinical significance. It is hypothesized that an optimizing of the strength of the quadriceps muscle may have a favorable effect on the postoperative rehabilitation program and shorten the period of convalescence.

Enrollment: 70 estimated patients

Sex: All

Ages: 18+ years old

Volunteers: No Healthy Volunteers

Inclusion criteria

• Planned TKA at the Aarhus University Hospital or Region Hospital Silkeborg,
• Living in Aarhus Municipality,
• Primary knee osteoarthritis or secondary osteoarthritis after meniscectomy or ligament injury

Exclusion criteria

• Unstable blood pressure,
• Neuromuscular or neurodegenerative disease,
• Comprehension or dementia problems

Trial design

Primary purpose: Treatment

Allocation: Randomized

Interventional model: Parallel Assignment

Masking: Single Blind

---

70 participants in 2 patient groups

Preoperative strength training

Experimental group

Description:

Progressive strength training on group basis four weeks before the operation and progressive strength training on group basis four weeks after the operation

Treatment:

Other: Preoperative strength training

Living as usual

No Intervention group

Description:

The patients are living as usual the last 4 weeks before operation