Preoperative TAP Block Versus Postoperative TAP Block in Patients Undergoing Laparoscopic Cholecystectomy: a Randomized Controlled Trial

University of Padova

Status: Enrolling

Conditions: TAP Block

Treatments: Procedure: Preoperative TAP Block; Procedure: Postoperative TAP block

Study type: Interventional

Funder types: Other

Identifiers

NCT06903182

6126/AO/24

Details and patient eligibility

About

The goal of this clinical trial is to learn if the regional anesthesia technique "TAP block" provide more analgesia when performed before or after the surgery. The main questions it aims to answer are:

Does preoperative TAP block provide greater analgesia than postoperative TAP block? Patients receiving preoperative TAP block will have less pain and take less painkillers than patients receiving postoperative TAP block?

Participants will:

Receive preoperative or postoperative TAP block They will be asked about their pain levels during the hospital stay.

Full description

The TAP block is a safe, easy-to-perform, and effective technique for managing postoperative pain. It reduces opioid consumption and increases patient satisfaction. Despite recent studies indicating that postoperative TAP block might be more effective than preoperative TAP block in reducing opioid use within 24 hours, the optimal timing of its administration (before or after surgery) remains unclear.

In this study we will compare preoperative to postoperative TAP block in patients undergoing laparoscopic cholecistectomy.

The primary aim of this study is to determine the difference in postoperative pain control between preoperative and postoperative TAP block administration in patients undergoing laparoscopic cholecystectomy.

The primary objective will be to evaluate the difference in postoperative pain at rest, 24 hours after surgery, between patients receiving preoperative versus postoperative TAP block. Pain will be assessed using the Numeric Rating Scale (NRS) from 0 to 10.

Secondary objectives will be intraoperative and postoperative opioids, postoperative nausea and vomiting, pain at resnt and on movement at 0,6,12,24 hours.

Enrollment: 46 estimated patients

Sex: All

Ages: 18+ years old

Volunteers: No Healthy Volunteers

Inclusion and exclusion criteria

Inclusion Criteria

• ASA I-II patients
• Age >18 years
• Informed consent

Exclusion Criteria

• History of chronic pain
• Beta-blocker therapy
• Allergy to the drugs used in the study

Trial design

Primary purpose: Treatment

Allocation: Randomized

Interventional model: Parallel Assignment

Masking: Double Blind

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46 participants in 2 patient groups

Preoperative TAP block

Experimental group

Description:

Patients will receive a preoperative TAP block with 40 mL (20 mL on the right side + 20 mL on the left side) of Ropivacaine 0.4%

Treatment:

Procedure: Preoperative TAP Block

Postoperative TAP block

Active Comparator group

Description:

Patients will receive a postoperative TAP block with 40 mL (20 mL on the right side + 20 mL on the left side) of Ropivacaine 0.4%

Treatment:

Procedure: Postoperative TAP block