Preoperative Topic Diclofenac as a Prevention of Postoperative Macular Edema in Patients With Diabetic Retinopathy

Eye Clinic Medic Zuljan Jukic

Status

Completed

Conditions

Cataract

Macular Edema

Diabetic Retinopathy

Treatments

Drug: placebo

Drug: Perioperative Diclofenac eye-drops administration

Study type

Interventional

Funder types

Other

Identifiers

NCT01694212

MZJ-2106

Details and patient eligibility

About

Diabetes has many negative effects on patients' general health. Among many other consequences it speeds up the cataract formation and that is why diabetic patients need cataract surgery very often. The known side effect of cataract surgery even in otherwise healthy patients is postoperative edema of the back of the eye (what causes decrease of vision), which has greater incidence especially in patients who have diabetic eye problems. The cause of that might be the intraocular inflammation which was previously demonstrated to be significantly more prominent in patients with untreated diabetic eye problems. Therefore we will examine if the 7 day use of anti-inflammatory eye drops prior to the cataract surgery prevent the formation of the edema of the back of the eye.

Enrollment

55 patients

Sex

All

Ages

60 to 90 years old

Volunteers

No Healthy Volunteers

Inclusion criteria

presence of nonproliferative diabetic retinopathy
presence of the cataract (LOCS 2-3)

Exclusion criteria

other chronic or acute eye diseases
hypersensitivity to any component of the diclofenac eye-drops patients on oral anticoagulant therapy
allergy to salycilates