Preoxygenation in the Intensive Care Unit Using a Nose-mouth Mask Versus High-flow Nasal Cannula Oxygen.

Universitätsklinikum Hamburg-Eppendorf

Status: Completed

Conditions: Respiratory Failure

Treatments: Device: Nose-mouth mask; Device: High flow nasal cannula oxygen; Procedure: Intubation

Study type: Interventional

Funder types: Other

Identifiers

NCT01994928

PV-4429

Details and patient eligibility

About

Preoxygenation is routinely performed before endotracheal intubation. In the intensive care unit, preoxygenation is often accomplished using a nose-mouth mask. It seems probable that high flow nasal cannula oxygen, which is used in the treatment of patients with hypoxemic respiratory failure, is equally effective in preventing the development of hypoxemia during intubation. In this prospective randomized study preoxygenation using high flow nasal cannula oxygen is compared with preoxygenation via nose-mouth mask in patients with hypoxemic respiratory failure.

Enrollment: 40 patients

Sex: All

Ages: 18+ years old

Volunteers: No Healthy Volunteers

Inclusion criteria

• patients treated in an intensive care unit
• indication for intubation
• presence of hypoxemic (SaO2/fraction of inspired oxygen(FiO2): 300 or less) respiratory failure
• informed consent

Exclusion criteria

• blocked nasopharynx
• contraindications for nose-mouth mask or high flow nasal cannula oxygen
• expected difficult airway

Trial design

Primary purpose: Treatment

Allocation: Randomized

Interventional model: Parallel Assignment

Masking: None (Open label)

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40 participants in 2 patient groups

Nose-mouth mask

Active Comparator group

Description:

Performance of intubation after preoxygenation using a nose-mouth mask.

Treatment:

Device: Nose-mouth mask

Procedure: Intubation

High flow nasal cannula oxygen

Experimental group

Description:

Performance of intubation after preoxygenation using high flow nasal cannula oxygen.

Treatment:

Device: High flow nasal cannula oxygen

Procedure: Intubation