Preoxygenation Using THRIVE Versus Facemask in Parturients

University of British Columbia

Status: Completed

Conditions: Preoxygenation

Treatments: Device: THRIVE preoxygenation; Device: Facemask preoxygenation

Study type: Interventional

Funder types: Other

Identifiers

NCT03772574

H18-02855

Details and patient eligibility

About

This study aims to determine the duration for pre-oxygenation using THRIVE and facemask for parturients.

Full description

We aim to determine the duration required for THRIVE and facemask preoxygenation in parturients for them to achieve ETO2 >90%.

Enrollment: 91 patients

Sex: Female

Ages: 19+ years old

Volunteers: Accepts Healthy Volunteers

Inclusion criteria

• Pregnant patients ≥36 weeks gestation.
• Non-laboring patients admitted for elective Cesarean delivery under neuraxial anesthesia or induction of labor.
• American Society of Anesthesiologists (ASA) class 2.

Exclusion criteria

• Any medical conditions that are likely to affect gas exchange.
• Obstructed nasal passage.
• Unable to tolerate a tight fitting facemask.
• Body Mass Index ≥40 kg/m2.
• Patients who are in active labor (i.e. cervical dilation ≥4cm).
• Patients who are unable to give informed consent.

Trial design

Primary purpose: Treatment

Allocation: Randomized

Interventional model: Parallel Assignment

Masking: Single Blind

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91 participants in 2 patient groups

THRIVE

Experimental group

Description:

THRIVE preoxygenation (tidal volume breathing with the OptiFlow system applied at 100% oxygen).

Treatment:

Device: THRIVE preoxygenation

Facemask

Active Comparator group

Description:

Facemask preoxygenation (tidal volume breathing via a face mask set at 100% oxygen).

Treatment:

Device: Facemask preoxygenation