Preoxygenation With Nasal Cannula and Noninvasive Positive Pressure Ventilation
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About
This is a prospective randomized cross over study of healthy volunteers comparing end-tidal oxygen concentration among subjects undergoing continuous positive airway pressure ventilation via a noninvasive ventilation (NIV) mask with and without the addition of nasal cannulas.
Full description
Noninvasive positive pressure ventilation with the addition of a nasal cannula is a useful technique to pre-oxygenate and provide apneic oxygenation in hypoxic patients undergoing emergency airway management. This study aims to evaluate preoxygenation by quantifying end-tidal oxygen (etO2) concentration resulting from nasal cannula placement underneath a noninvasive positive pressure ventilation (NIPPV) mask. This is a prospective randomized cross over study of healthy volunteers undergoing continuous positive airway pressure ventilation via a noninvasive ventilation (NIV) mask with and without the addition of nasal cannulas. End-tidal oxygen concentration will be measured by an oxygen sensor following three minutes of NIPPV with and without the addition of a nasal cannula, with each subject serving as his or her own control.
Enrollment
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Volunteers
Inclusion criteria
- Any healthy volunteer aged 18-65 years.
Exclusion criteria
- Previous inability to tolerate noninvasive positive pressure ventilation with addition of a nasal cannula.
- Known underlying cardiac or pulmonary disease.
- Active respiratory infections.
Trial design
Primary purpose
Allocation
Interventional model
Masking
37 participants in 2 patient groups
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Data sourced from clinicaltrials.gov
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