Preparative Fasting Before Contrast-enhanced Computed Tomography

HaEmek Medical Center, Israel

Status: Completed

Conditions: X-ray Contrast Media Adverse Reaction

Study type: Observational

Funder types: Other

Identifiers

NCT03533348

0167-17-EMC

Details and patient eligibility

About

The study aims to determine whether there is a need for preparative fasting prior to contrast-enhanced computed tomography (CT).

Full description

The use of fasting orders for imaging and other procedures is common, this seemingly benign practice can lead to real harms to patients and poor satisfaction with their care. The nothing per os (NPO) order is sometimes used in CT scans because gastrointestinal tract contents can interrupt visualization of the intestinal lumen, but more commonly NPO orders are are thought to protect all supine patients from aspiration during delivery of intravenous contrast. There is limited evidence to support such practice of NPO orders prior to contrast-enhanced CT scans. The authors' main objective is to determine if there is a need for preparative fasting prior to contrast-enhanced CT scans.

Enrollment: 2,148 patients

Sex: All

Ages: 18+ years old

Volunteers: No Healthy Volunteers

Inclusion criteria

• Patients undergoing contrast-enhanced CT scans

Exclusion criteria

1. Pateints undergoing CT scans while sedated.

2. Patients under the age of 18 years

3. Patients who suffer from a mental disorder that prevents them:

   1. from understanding what s/he consents to and/ or
   2. from choosing decisively and/ or
   3. from communicating his/her consent

4. Patients who were instructed not to eat due to requirements of a specific study (for example.. computed tomography enterography-CTE)

Trial design

2,148 participants in 2 patient groups

Fasting arm

Description:

Patients will need at least 4 hours of fasting prior to contrast-enhanced CT scans.

No fasting

Description:

Patients are allowed to eat and drink freely prior to contrast-enhanced CT scans.