Presence of IBD Specific Antibodies (ASCA, ALCA, ACCA, AMCA) in the Sera of Patients With Spondyloarthropathy

Tel Aviv Sourasky Medical Center

Status: Unknown

Conditions: Psoriatic Arthritis; Undifferentiated Spondyloarthropathy; Ankylosing Spondylitis

Study type: Observational

Funder types: Other

Identifiers

NCT00517101

TAMSC-07-VA-318-CTIL

Details and patient eligibility

About

A relationship between IBD and spondyloarthropathy is well recognized. ASCA ( anti saccharomyces cerevisiae antibodies)are considered to be a serological marker for Crohn's disease and have been studied in patients with spondyloarthropathy with conflicting results. More recently, new serological markers for IBD have been described. These markers are antibodies to certain defined glycans , and their use may permit an improved diagnosis of IBD.

The aim of our study is to investigate wether these new serological markers are present in the sera of patients with spondyloarthropathy.

Sex: All

Ages: 18+ years old

Volunteers: Accepts Healthy Volunteers

Inclusion criteria

• diagnosis of psoriatic arthritis, ankylosing spondylitis, or undifferentiated spondyloarthropathy

Exclusion criteria

• diagnosed inflammatory bowel disease