Presence of Minor Anti Phospholipid Antibodies in Blood Samples of Ischemic Stroke Patients and Healthy Controls

Clalit Health Services

Status: Unknown

Conditions: Ischemic Stroke

Study type: Observational

Funder types: Other

Identifiers

NCT01487746

0125-11-MMC

Details and patient eligibility

About

The investigators expect to find higher levels of both classical and minor antiphospholipid (APL) antibodies among the stroke cases. Furthermore, the investigators expect to find not only classical APLA but also minor antibodies.

The investigators believe that minor antibodies have a major role in the hypercoagulability state.

Enrollment: 207 estimated patients

Sex: All

Ages: 18+ years old

Volunteers: Accepts Healthy Volunteers

Inclusion criteria

• stroke diagnosis
• blood sampling within 36hrs from the event
• written agreement

Exclusion criteria

• a stroke, MI or major operation prior to the current stroke
• hypercoagulable state known in this patient
• a severe chronic disease known at the time of the stroke
• an infection on arrival (based on anamnesis, physical exam and lab tests)
• thrombolytic treatment

Trial design

207 participants in 2 patient groups

treatment

Description:

Stroke patients

Controls

Description:

healthy controls