Presentation and Outcomes of Acute Appendicitis During COVID Pandemic (AA)

Mansoura University

Status: Completed

Conditions: Acute Appendicitis

Treatments: Procedure: appendectomy

Study type: Interventional

Funder types: Other

Identifiers

NCT05104346

acute appendicitis (AA)

Details and patient eligibility

About

Acute appendicitis (AA) is a frequent cause of acute abdominal pain in emergency rooms around the world [1]. The lifetime risk of developing AA is estimated to be about 8% [1-3]. The severe acute respiratory syndrome SARS-CoV-2 Coronavirus (COVID-19) pandemic has raised difficult situations for healthcare systems and organizations around the world, with direct and indirect implications for patient care delivery. COVID-19 causes a wide range of clinical symptoms, including fever, dry cough, myalgia, and exhaustion, with pulmonary involvement in many cases. According to the World Health Organization (WHO), The effect of the COVID-19 pandemic on acute appendicitis and surgical care is unknown due to a lack of evidence. To see how appendicitis care has changed as a result of the COVID-19 pandemic, this study compares clinical presentation, investigative modalities, treatment procedures, and outcomes before and after the pandemic.

Full description

Acute appendicitis (AA) is a frequent cause of acute abdominal pain in emergency rooms around the world [1]. The lifetime risk of developing AA is estimated to be about 8% [1-3]. The SARS-CoV-2 Coronavirus (COVID-19) pandemic has raised difficult situations for healthcare systems and organizations around the world, with direct and indirect implications for patient care delivery. COVID-19 causes a wide range of clinical symptoms, including fever, dry cough, myalgia, and exhaustion, with pulmonary involvement in many cases. According to the World Health Organization (WHO), The effect of the COVID-19 pandemic on acute appendicitis and surgical care is unknown due to a lack of evidence. To see how appendicitis care has changed as a result of the COVID-19 pandemic, this study compares clinical presentation, investigative modalities, treatment procedures, and outcomes before and after the pandemic. This is a multicenter prospective cohort study that was conducted for patients presented with Acute Appendicitis (AA).

Enrollment: 1,945 patients

Sex: All

Ages: 12+ years old

Volunteers: No Healthy Volunteers

Inclusion criteria

patients with acute appendicitis

Exclusion criteria

• patients with acute appendicitis less than 12 years
• malignant appendix

Trial design

Primary purpose: Treatment

Allocation: Non-Randomized

Interventional model: Parallel Assignment

Masking: Double Blind

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1,945 participants in 2 patient groups, including a placebo group

Patients in group I (G1) had AA prior to the era of COVID

Placebo Comparator group

Description:

Patients in group I (G1) had AA prior to the era of COVID

Treatment:

Procedure: appendectomy

patients in group II (G2) had AA during COVID

Active Comparator group

Description:

patients in group II (G2) had AA during COVID

Treatment:

Procedure: appendectomy