Preservation of Fat Free Mass During Weight Loss

University of Aarhus

Status: Completed

Conditions: Muscle Loss

Treatments: Other: walking program; Dietary Supplement: Whey protein supplementation; Other: Very Low Calorie Diet

Study type: Interventional

Funder types: Other

Identifiers

NCT03102372

Section of Sport Science, AU

Details and patient eligibility

About

In this study, we aimed to examine the effect of whey protein supplementation given before night sleep on Fat Free Mass (FFM) preservation during a 4 wk period on Very Low Caloric Diet (VLCD).

Half of the participants underwent a 4 week VLCD and walking program, while the other half underwent a 4 week VLCD, walking program and had an additional protein supplement before each night sleep.

Enrollment: 29 patients

Sex: All

Ages: 18 to 55 years old

Volunteers: Accepts Healthy Volunteers

Inclusion criteria

• Body Mass Index (kg/m^2) > 28
• Age between 18 and 55 years

Exclusion criteria

• Participation in regular resistance-, aerobic- or anaerobic training (>1 h/wk within the last 3 month before intervention start)
• Diabetes Physical disabilities that would hinder completion of the walking program.

Trial design

Primary purpose: Basic Science

Allocation: Randomized

Interventional model: Parallel Assignment

Masking: Single Blind

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29 participants in 2 patient groups, including a placebo group

Protein group

Experimental group

Description:

4 weeks of a Very Low Calorie Diet (VLCD) + walking program. Whey protein supplementation 0.4g/kg before sleep.

Treatment:

Other: walking program

Dietary Supplement: Whey protein supplementation

Other: Very Low Calorie Diet

Placebo group

Placebo Comparator group

Description:

4 weeks of a Very Low Calorie Diet (VLCD) + walking program

Treatment:

Other: walking program

Other: Very Low Calorie Diet