Preserving Left Colonic Artery During Radical Resection of Rectal Cancer

Third Military Medical University

Status and phase: Completed; Phase 3

Conditions: Postoperative Complications; Proteinosis

Treatments: Procedure: The left colonic artery is not preserved; Procedure: Preserve the left colonic artery

Study type: Observational

Funder types: Other

Identifiers

NCT03776370

20181155

Details and patient eligibility

About

To evaluate the feasibility and clinical significance of preserving left colonic artery in rectal cancer surgery.The investigators will focus on the effect of preserving left colonic artery during radical resection of rectal cancer on anastomotic leakage and oncology efficacy.

Full description

The investigators performed three-dimensional (3D) reconstruction to investigate the vascular anatomy, including the inferior mesenteric artery (IMA) and left colic artery (LCA),to help make pre-operative strategies of rectal cancer surgery.The investigators will preserving the left colonic artery during rectal cancer surgery and evaluate its feasibility and clinical significance.The investigators will focus on the effect of preserving left colonic artery during radical resection of rectal cancer on anastomotic leakage and oncology efficacy.

Enrollment: 200 patients

Sex: All

Ages: 18 to 80 years old

Volunteers: No Healthy Volunteers

Inclusion criteria

1. Pathological biopsy confirmed adenocarcinoma of the rectum；
2. Preoperative assessment of tolerance to surgery without major organ dysfunction；
3. Patients must be able to understand and voluntarily sign written informed consent；
4. The surgical method is laparoscopic or robotic anterior rectal cancer resection.

Exclusion criteria

1. The patient cannot tolerate the operation；
2. Refusal to sign informed consent；
3. Patients with distant metastasis of rectal cancer；
4. The surgical method was changed to miles or Hartman;
5. Unable to complete the follow - up

Trial design

200 participants in 2 patient groups

Preserve the left colonic artery

Description:

Preservation of left colonic artery in rectal cancer surgery.

Treatment:

Procedure: Preserve the left colonic artery

The left colonic artery is not preserved

Description:

The left colonic artery was dissected in rectal cancer surgery

Treatment:

Procedure: The left colonic artery is not preserved