Pressure Controlled Ventilation Versus Volume Controlled Ventilation in Upper Abdominal Surgery

Istanbul University

Status: Completed

Conditions: Ventilator Lung

Treatments: Other: Starting with pressure controlled ventilation and changing the ventilation mode every 20 minutes; Other: Starting with volume controlled ventilation and changing the ventilation mode every 20 minutes

Study type: Interventional

Funder types: Other

Identifiers

NCT05690867

2021-2081

Details and patient eligibility

About

Comparison of mechanical powers produced at volume controlled and pressure controlled mechanical ventilation

Full description

The mechanical power created by mechanical ventilation, as a new concept, can enable to evaluate the effect of different components in the lung.Our aim in this study is to calculate mechanical power in different ventilation modes ( pressure controlled and volume controlled ventilation) and to compare them. To calculate the mechanical powers we will use Van der Meijden's mechanical power formula for pressure controlled ventilation and for volume controlled ventilation we will use Gattinoni's mechanical power formula. In the literature we haven't seen any publication comparing the mechanical power of two commonly used ventilation modes (volume controlled and pressure controlled ventilation)

Enrollment: 60 patients

Sex: All

Ages: 18+ years old

Volunteers: Accepts Healthy Volunteers

Inclusion criteria

• ASA1-2 , >18 years old patients having upper abdominal surgery

Exclusion criteria

• chronic obstructive lung disease, interstitial lung disease
• chronic renal failure
• Child-Pugh > 6 liver disease
• Patients who don't give consent
• NYHA > 2 heart failure

Trial design

Primary purpose: Other

Allocation: Randomized

Interventional model: Crossover Assignment

Masking: None (Open label)

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60 participants in 2 patient groups

Group 1

Other group

Description:

group 1 starts with volume controlled ventilation

Treatment:

Other: Starting with volume controlled ventilation and changing the ventilation mode every 20 minutes

Group 2

Other group

Description:

group 2 starts with pressure controlled ventilation

Treatment:

Other: Starting with pressure controlled ventilation and changing the ventilation mode every 20 minutes