Pressure Levels on Lung Expansion

Universidade Cidade de Sao Paulo

Status: Completed

Conditions: Pleural Effusion

Treatments: Device: Noninvasive positive airway pressure with different levels

Study type: Interventional

Funder types: Other

Identifiers

NCT03027180

UNICID/CNPq 442709/2014-5

Details and patient eligibility

About

Question: What level of noninvasive positive airway pressure is able to expand the lungs of people with pleural drainage? Design: Cross-sectional, experimental and randomized study. Participants: Four consecutive people with pleural effusion drained within 24 hours, with controlled pain and without contraindications to use of noninvasive positive pressure. Intervention: Each person will be randomly subjected to three levels of noninvasive positive airway pressure: 0 (zero), 4 and 15 cmH2O for evaluation via chest computed tomography. Outcome measures: Lung area.

Enrollment: 4 patients

Sex: All

Ages: 18+ years old

Volunteers: No Healthy Volunteers

Inclusion criteria

• age over 18 years
• presence of pleural drainage after traumatic hemothorax
• thoracic drainage within 24 hours
• controlled pain (below 3 points in the visual numeric scale, varying from zero to ten)

Exclusion criteria

• contraindication for use of noninvasive positive pressure in the airways, such as reduced level of consciousness (drowsiness, agitation or confusion), use of vasoactive drugs, complex arrhythmias, upper airway obstruction or trauma in the face, esophagus or upper airway, ineffective cough, inability to swallow, distended abdomen, nausea, vomiting, upper gastrointestinal bleeding
• previous application of any sort of lung expansion technique after thoracic drainage.

Trial design

Primary purpose: Treatment

Allocation: Randomized

Interventional model: Crossover Assignment

Masking: Single Blind

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4 participants in 3 patient groups

0 (zero) cmH2O

Active Comparator group

Description:

After draining, people will be asked about the level of pain via visual numeric scale and then subjected to chest computed tomography (Aquilion 64-Toshiba Medical Systems®, Japan), using positive airway pressure in the airways with 0 cmH2O

Treatment:

Device: Noninvasive positive airway pressure with different levels

4 cmH2O

Experimental group

Description:

After draining, people will be asked about the level of pain via visual numeric scale and then subjected to chest computed tomography (Aquilion 64-Toshiba Medical Systems®, Japan), using positive airway pressure in the airways with 4 cmH2O

Treatment:

Device: Noninvasive positive airway pressure with different levels

15 cmH2O

Experimental group

Description:

After draining, people will be asked about the level of pain via visual numeric scale and then subjected to chest computed tomography (Aquilion 64-Toshiba Medical Systems®, Japan), using positive airway pressure in the airways with 15 cmH2O

Treatment:

Device: Noninvasive positive airway pressure with different levels