PREsurgical Cognitive Evaluation Via Digital clockfacEdrawing (PRECEDE)

University of Florida

Status: Enrolling

Conditions: Cognitive Dysfunction

Treatments: Behavioral: digital cognitive testing

Study type: Observational

Funder types: Other; NIH

Identifiers

NCT03175302

IRB201700747-N

OCR18881 (Other Identifier)

R01AG055337 (U.S. NIH Grant/Contract)

Details and patient eligibility

About

This study leverages a modernized digital version of a well-known cognitive screening tool to examine pre and post operative cognitive function after surgery in adults age 65 years or more. Machine learning algorithms will be applied to the hospital wide standard of care cognitive metric to identify risk for post-operative cognitive complications.

Full description

This proposal innovatively leverages a brief but informative digital test with machine learning to examine the subtlety of pre-surgery cognition within an extremely large number of older individuals screened preoperatively within an academic tertiary medical center. It also incorporates a unique group of well characterized non-surgery peers for demographic matching to assist with normal versus abnormal machine learning analyses.

Enrollment: 25,240 estimated patients

Sex: All

Ages: 65+ years old

Volunteers: No Healthy Volunteers

Inclusion criteria

• >/= 65 years of age
• screening within the University of Florida (UF) Health Preoperative clinic
• presurgical cognitive screening with the digital Clock Drawing Tool (dCDT)

Exclusion criteria

• < 65 years of age
• did not complete screening within the UF Health Preoperative clinic
• did not complete the presurgical cognitive screening with the digital Clock Drawing Tool (dCDT)

Trial design

25,240 participants in 2 patient groups

Surgical group

Description:

Baseline preoperative digital cognitive testing performance in adults to predict frequency and severity of clinician reported outcomes within the first three months post-surgery.

Treatment:

Behavioral: digital cognitive testing

Control

Description:

Non-surgery matched peers with the same testing.

Treatment:

Behavioral: digital cognitive testing