Prevalence and Dynamic of Sleep-disordered Breathing in Patients Pre and Post Heart Transplantation (HTx-HDZ-SDB-1)

Heart and Diabetes Center North-Rhine Westfalia

Status: Completed

Conditions: Sleep Disordered Breathing Central; Heart Failure; Heart Transplantation

Treatments: Behavioral: Sleep-disordered breathing

Study type: Observational

Funder types: Other

Identifiers

NCT03026634

PDSAP-HTX

Details and patient eligibility

About

Sleep-disordered breathing is believed to appear at a high prevalence in end-stage heart failure patients and the presence of sleep-disordered breathing has been associated with increased mortality. This study is designed to investigate prevalence and dynamics of sleep-disordered breathing in end-stage heart failure patients pre and post heart transplantation.

Full description

Sleep-disordered breathing is believed to appear at a high prevalence in end-stage heart failure patients and the presence of sleep-disordered breathing has been associated with increased mortality. This study is designed to investigate prevalence and dynamics of sleep-disordered breathing in end-stage heart failure patients pre and post heart transplantation, as this topic is hardly studied yet and previous reports suggest changes in the entity of sleep-disordered breathing through heart transplantation. The circumstances and the impact of sleep-disordered breathing or residuals in heart transplant patients is not well understood yet and will be subject of this study.

Enrollment: 500 patients

Sex: All

Ages: 18 to 70 years old

Volunteers: No Healthy Volunteers

Inclusion criteria

• End-stage heart failure patients assigned and eligible for heart transplantation

Exclusion criteria

• heart failure patients not eligible for heart transplantation