Prevalence and Factors of Sarcopenia and in Patients With Primary Sjogren's Syndrome

Acibadem University

Status: Completed

Conditions: Sjogren's Syndrome; Rheumatologic Disease; Sarcopenia

Treatments: Other: Sarcopenia Assessment

Study type: Observational

Funder types: Other

Identifiers

NCT05015114

ATADEK - 2021/10

Details and patient eligibility

About

Sarcopenia is a progressive condition characterized by decline in muscle strength and muscle mass. Although the mechanism of sarcopenia has not been fully elucidated, it may be caused by protein-poor diet, vitamin D deficiency, hormonal changes, increase in inflammatory cytokine level and oxidative stress. For this reason, it is thought that determining the prevalence of sarcopenia in rheumatological diseases with chronic inflammation and protecting patients from possible comorbidities with appropriate interventions may be an important factor in maintaining and improving the functional levels and quality of life of patients.

The aim of our study was to investigate the prevalence and its associated factors of sarcopenia in individuals with primary Sjögren's Syndrome.

Enrollment: 50 patients

Sex: All

Ages: 40 to 70 years old

Volunteers: No Healthy Volunteers

Inclusion criteria

• Diagnosed with primary Sjogren's syndrome by an experienced rheumatologist according to European League Against Rheumatism (EULAR) ve American College of Rheumatology (ACR) criteria
• Being 40 years or older.

Exclusion criteria

• Pregnancy,
• Malignancy,
• Presence of other rheumatological diseases,
• Presence of diabetes mellitus
• Presence of neurological problems
• Presence of osteoarthritis

Trial design

50 participants in 2 patient groups

Primary Sjogren's Syndrome

Description:

Participants with Primary Sjogren's Syndrome

Treatment:

Other: Sarcopenia Assessment

Control group

Description:

Healthy controls

Treatment:

Other: Sarcopenia Assessment