Prevalence and Genetic Alternation of Autoimmune Polyglandular Syndrome Type II in Taiwan

National Taiwan University

Status: Enrolling

Conditions: Autoimmune Polyendocrine Syndrome Type II

Treatments: Other: no intervention

Study type: Observational

Funder types: Other

Identifiers

NCT05578105

202112250RINC

Details and patient eligibility

About

Autoimmune polyendocrine syndrome (APS) is an autoimmune disease involving at least two endocrine organ. It is classified into type I and type II diseases. Among them, APS type II is more common. It is diagnosed when two of the three following diseases are diagnosed in the same patient, including type 1 diabetes mellitus, autoimmune thyroid disease, and primary adrenal insufficiency. In this study, we will observe the epidemiology, clinical characteristics, and genetic variants of APS II in Taiwan.

Enrollment: 650 estimated patients

Sex: All

Ages: 20+ years old

Volunteers: No Healthy Volunteers

Inclusion criteria

• Patients visited NTUH during 2006-2021, and had at least two of the three diseases: type 1 DM, primary adrenal insufficiency, and autoimmune thyroid disease.

Exclusion criteria

• Patients aged less than 20 years old

Trial design

650 participants in 1 patient group

Autoimmune polyendocrine syndrome type II

Description:

patients with autoimmune polyendocrine syndrome type II

Treatment:

Other: no intervention