Prevalence and Incidence of Central Airway Obstruction in Advanced Lung Cancer

Maggiore Bellaria Hospital, Bologna

Status: Terminated

Conditions: Lung Cancer

Study type: Observational

Funder types: Other

Identifiers

NCT01799395

13002-Trisolini

Details and patient eligibility

About

Lung cancer may cause central airway obstruction through several different mechanisms (invasion by the primary tumor, invasion by metastatic lymph nodes, airway metastasis).

The aim of the present study is to determine the prevalence at the time of diagnosis, the incidence at 1 year from the diagnosis, and the predictors of central airway obstruction associated with advanced lung cancer.

Enrollment: 45 patients

Sex: All

Ages: 18 to 85 years old

Volunteers: No Healthy Volunteers

Inclusion criteria

• Advanced lung cancer with indication for chemotherapy or chemotherapy + radiation therapy

Exclusion criteria

• Age < 18 year
• Pregnancy
• Refusal to sign informed consent

Trial design

45 participants in 1 patient group

Lung Cancer

Description:

All patients with advanced lung cancer candidate for chemotherapy or chemotherapy + radiation therapy will be enrolled and followed-up for 1 year clinically and radiologically (Chest CT) to verify whether or not central airway obstruction is present at the time of diagnosis or occurs in the year following diagnosis (or in the life span from diagnosis and death in patients who die before 1 year of diagnosis). Furthermore, predictor variables possibly associated with central airway obstruction will be studied.