Prevalence and Reversibility of Lung Hyperinflation in Asthma (Dist'air2)

Chiesi

Status: Completed

Conditions: Asthma

Study type: Observational

Funder types: Industry

Identifiers

NCT01573364

EQFST5213

Details and patient eligibility

About

The aim of this observational study is to evaluate the pulmonary hyperinflation and its immediate reversibility to a short acting beta2 agonist test in uncontrolled persistent asthmatic patients with dyspnea.

Full description

The other objectives are :

• the evaluation of the hyperinflation defined by an increase of the residual volume (RV),
• the observation of the relationship between the hyperinflation and the asthma characteristics,
• the study of the improvement of the functional parameters after a reversibility test
• the evaluation of the correlation between hyperinflation parameters evolution, chest tightness and dyspnea

Enrollment: 450 patients

Sex: All

Ages: 18 to 90 years old

Volunteers: No Healthy Volunteers

Inclusion criteria

• Patient with a diagnosis of uncontrolled persistent asthma (ACT </= 19) or with an MRC score of dyspnea >/= 1
• Patient requiring a check-up including a pulmonary function test by plethysmography with a reversibility test

Exclusion criteria

• Patient participating to an other clinical trial or having participated to a clinical trial with medicine in the last 3 months