Prevalence and Risk Evaluation of Diabetic Complications of the Foot in A Large Canadian Population (PEDAL)

LMC Diabetes & Endocrinology Ltd.

Status: Completed

Conditions: Foot Ulcer, Diabetic; Neuropathy, Diabetic; Diabetes Mellitus, Type 1; Hyperkeratosis; Onychauxis; Foot Deformities; Diabetes Mellitus, Type 2; Onychomycosis

Study type: Observational

Funder types: Other

Identifiers

NCT04327622

PEDAL

Details and patient eligibility

About

The study aims to assess foot complications among patients with diabetes in Canada, using patient data collected during diabetes foot assessments performed by the LMC Chiropody Team between February 27, 2018 and April 17, 2019.

Full description

Among patients with diabetes, one of the major causes of increased morbidity and mortality include lower-extremity complications. Patients who have peripheral neuropathy and peripheral arterial disease are at risk of developing foot ulcers and infection, which can lead to lower-extremity amputations. Adults with diabetes in Canada are 20 times more likely to be hospitalized for a nontraumatic lower limb amputation than adults without diabetes. Thus, the prevention, education and early treatment of diabetes foot complications are an important component of caring for patients living with diabetes.

In addition to neuropathy and peripheral arterial disease, risk factors for developing foot ulcers include increased levels of glycated hemoglobin, onychomycosis, microvascular complications, previous foot ulcer or amputation, structural deformity, and limited joint mobility. To the best of our knowledge, the prevalence of foot complications, such as onychomycosis, and the association of diabetes foot complications with glycemic control and other diabetes risk factors, has not been assessed before in a large sample of Canadian patients. To better understand foot complications among patients with diabetes in Canada, the investigators will retrospectively examine patient data collected during diabetes foot assessments performed by the LMC Chiropody Team. The LMC Chiropody Team is part of LMC Diabetes & Endocrinology, which is one of the largest endocrine practice groups globally.

Enrollment: 5,084 patients

Sex: All

Ages: 18+ years old

Volunteers: No Healthy Volunteers

Inclusion criteria

• Age ≥ 18 years
• Diagnosis of type 1 or type 2 diabetes
• Under the care of an endocrinologist at LMC
• Diabetes foot assessment was performed by the LMC Chiropody Team
• Informed consent to use patient medical record data for research purposes was provided

Exclusion criteria

• Prior diabetes foot assessment by an LMC chiropodist