Prevalence and Risk Factor of NP in Women With LUTS

National Taiwan University

Status: Completed

Conditions: Lower Urinary Tract Symptoms

Study type: Observational

Funder types: Other

Identifiers

NCT04104100

201907002RIN

Details and patient eligibility

About

The knowledge of prevalence and risk factors of nocturnal polyuria might be important for the treatment of women with lower urinary tract symptoms (LUTS). Thus, our aim is to describe the prevalence and risk factors of nocturnal polyuria in women with LUTS.

Full description

Between September 2010 and January 2019, all women with LUTS visiting urogynecological department of a medical center for urodynamic evaluation were reviewed. Nocturnal polyuria was defined when the proportion of night-time voided volume over 24-hour voided volume was greater than 33% for ≥65 year-old women, and when the proportion of night-time voided volume over 24-hour voided volume was greater than 20% for <65 year-old women. Backward stepwise multivariable logistic regression analysis was performed using all statistical variables in the univariate logistic regression analysis. P < 0.05 was considered as statistical significant.

Enrollment: 3,000 patients

Sex: Female

Ages: 20 to 85 years old

Volunteers: No Healthy Volunteers

Inclusion criteria

• Women with lower urinary tract symptoms
• Complete a 3-day bladder diary

Exclusion criteria

• <20 y/o or > 85 y/o
• Regular urethral catheterization or intermittent self-catheterization
• Urinary tract infection or chronic inflammation in the previous 2 weeks
• Bladder calculus
• Neurogenic bladder due to radical hysterectomy or injury of the central nervous system
• History of pelvic radiotherapy or a preexisting malignant pelvic tumor.

Trial design

3,000 participants in 2 patient groups

Women with nocturnal polyuria

Description:

Nocturnal polyuria was defined when the proportion of night-time voided volume over 24-hour voided volume was greater than 33% for ≥65 year-old women, and when the proportion of night-time voided volume over 24-hour voided volume was greater than 20% for \<65 year-old women.

Women without nocturnal polyuria

Description:

Nocturnal polyuria was defined when the proportion of night-time voided volume over 24-hour voided volume was greater than 33% for ≥65 year-old women, and when the proportion of night-time voided volume over 24-hour voided volume was greater than 20% for \<65 year-old women.