Prevalence and Risk Factors for Coxiella Burnetii Seropositivity (Q Fever) Among Adults in Western France (MEDVETFQ)

Nantes University Hospital (NUH)

Status: Unknown

Conditions: Q Fever

Treatments: Other: blood test

Study type: Observational

Funder types: Other; Industry

Identifiers

NCT03334019

RC16_0420

Details and patient eligibility

About

Diseases naturally transmitted between animals and humans (zoonoses) are one of the leading causes of emergence or re-emergence of human infectious diseases. Non-foodborne zoonoses are commonly transmitted to human directly by contact with infected animals or contaminated environment. People working with animals such as farmers and veterinarians are particularly at risk of infection. Some zoonoses can also be transmitted indirectly thought the air and therefore can affect the general population. Example is Q fever, a disease caused by Coxiella burnetii, a bacterium highly resistant in the environment.

In Western France, Q fever is endemic in cattle herds. To improve human zoonotic disease surveillance, the investigators will conduct a population based study in this area.

The aims of the study are:

1. To assess seroprevalence of Coxiella burnetii infection among general population, farmers and veterinarians in Western France
2. To identify risk factors for Coxiella burnetii seropositivity in these populations

Full description

In order to estimate seroprevalence and risk factors for Coxiella burnetii infection in humans, the investigators will conduct a cross-sectional study in three groups:

blood donors at blood donation organizations (general population) beef and dairy cattle farmers veterinarians involved in a rural practice

All the participants in the study will provide a blood sample and will fill in a questionnaire.

Enrollment: 559 estimated patients

Sex: All

Ages: 18+ years old

Volunteers: Accepts Healthy Volunteers

Inclusion criteria

• Give a written informed consent
• Be 18 years old and over
• Be able to speak French

Exclusion criteria

• Adults under protection (guardianship or curators)
• Contraindication for drawing blood

Trial design

559 participants in 1 patient group

subjects

Description:

Data collected on general population, farmers and veterinarians though questionnaires and blood samples.

Treatment:

Other: blood test