Prevalence of a Localized or Diffuse Pruritus in a Population With One or Several, Primitive or Secondary, Brain Tumor(s) (PRURI-C)

Regional University Hospital Center (CHRU)

Status: Completed

Conditions: Brain Tumor; Pruritus

Study type: Observational

Funder types: Other

Identifiers

NCT03673878

29BRC18.0155

Details and patient eligibility

About

The association between the presence of pruritus, especially centrofacial, and the presence of a brain tumor is a widespread notion in the medical community but based on a single publication by Andreev et al. in the British Journal of Dermatology published in 1975. No other study has studied this association with a rigorous methodology. The aim of this study is to evaluate the prevalence of pruritus in patients with one or more primary or secondary brain tumor(s), benign(s) or malignant(s).

Full description

• Monocentric prospective observational study
• On the inclusion period
• Patients who are seen in radiotherapy consultation and / or department of neurosurgery
• Complying with the inclusion criteria, not falling within the exclusion criteria
• Re-reading of cerebral MRI (cMRI) with precision on the location(s) of the brain tumor(s) according to a predefined anatomic descriptive diagram
• Complete the questionnaire by a dermatologist (characteristics of pruritus, brain lesion(s), characteristics of the population)

Enrollment: 200 patients

Sex: All

Ages: 18+ years old

Volunteers: No Healthy Volunteers

Inclusion criteria

• Age > 18 years
• Diagnosis of benign or malignant brain tumor, primary or secondary.
• Accepted non-opposition
• Realization of a cerebral MRI (cMRI)

Exclusion criteria

• Age < 18 years
• Absence of cerebral imaging of the cMRI type
• Absence of non opposition
• Realization of a treatment modifying the brain structure (radiotherapy / surgery)