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Prevalence of Abnormal Postures in Parkinson's Disease (POSTUREinPD)

U

University of Verona

Status

Unknown

Conditions

Parkinson Disease

Study type

Observational

Funder types

Other

Identifiers

NCT03573232
Università di Verona

Details and patient eligibility

About

Postural abnormalities represent disabling and painful complications in patients with Parkinson's disease (PD). The stooped posture is a typical feature of PD but with advancing of disease more severe body abnormalities can affect people with PD. These deformities include Pisa syndrome, camptocormia, antecollis, scoliosis and striatal deformities related to hand (striatal hand) and/or toes (striatal toes).

Full description

Postural abnormalities represent disabling and painful complications in patients with Parkinson's disease (PD). The first postural trunk deviation in PD was first described by James Parkinson himself and recognized as stooped simian appearance, with flexion of the hips and knees, and rounding of the shoulders. Although the stooped posture is a typical feature, more severe spinal misalignment (and deformities) can affect people with PD. These postural deformities include Pisa syndrome (PS), camptocormia (CP), antecollis (AC), scoliosis (S) and striatal deformities related to hand (striatal hand) and/or toes (striatal toes). The prevalence of these postural deformities is variable because several diagnostic criteria have been used to characterize each deformity. Recently, a consensus of diagnostic criteria has been reached in literature permitting us to better mapping the presence of these deformities in people with PD.

Enrollment

794 estimated patients

Sex

All

Ages

18+ years old

Volunteers

No Healthy Volunteers

Inclusion criteria

  1. Participants will be considered enrolled after signing the consent form;
  2. Diagnosis of Parkinson's disease;

Exclusion criteria

  1. Concomitant neurologic diseases known to negatively affect posture;
  2. A history of major spinal surgery or muscle and/or skeletal diseases;
  3. Treatment with drugs potentially able to induce abnormal postures;
  4. Clinical features consistent with a diagnosis of atypical parkinsonism;

Trial contacts and locations

7

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Central trial contact

Christian Geroin, PhD; Michele Tinazzi, MD, PhD, Professor

Data sourced from clinicaltrials.gov

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