Prevalence of Acute Critical Neurological Disease in Children: a Global Epidemiological Assessment (PANGEA)

University of Pittsburgh

Status: Completed

Conditions: Hydrocephalus; Status Epilepticus; Traumatic Brain Injury; Stroke; Spinal Cord Disease; Cardiac Arrest; Brain Mass

Treatments: Other: No intervention

Study type: Observational

Funder types: Other; Industry

Identifiers

NCT02381977

PANGEA

Details and patient eligibility

About

PANGEA is an international prospective point prevalence study to describe the epidemiology, interventions, and outcomes in children with acute critical brain disease.

Enrollment: 922 patients

Sex: All

Ages: 7 days to 17 years old

Volunteers: No Healthy Volunteers

Inclusion criteria

1. Children aged 7 days to 17 years inclusively and admitted to an ICU (ICU can be classified as general, cardiac, trauma, etc).
2. Children with acute or acute on chronic neurologic disease that occurred just prior to hospital admission or occurred during the hospital admission.
3. Acute neurologic disease is secondary to TBI, stroke, brain mass, hydrocephalus, cardiac arrest, status epilepticus, CNS infection/inflammation, or spinal cord injury.

Exclusion criteria

1. Children with acute perinatal neurologic disease.
2. Children with isolated chronic brain injury and no acute neurologic disease.