Prevalence of Advanced Fibrosis in Patients Living With HIV (FLASH)

Johannes Gutenberg University (JGU)

Status: Invitation-only

Conditions: Fatty Liver Disease

Study type: Observational

Funder types: Other

Identifiers

NCT04066608

18-00379

Details and patient eligibility

About

Monocentric, cross-sectional study to define the prevalence of advanced fibrosis in an HIV infected outpatient population. Follow-up over 10 years to assess clinical relevance.

Full description

Globally a shift in the spectrum of diseases has occurred. While in earlier year's infectious (communicable) disease were the main contributors to morbidity and mortality, today non-communicable diseases (NCD) exhibit a dramatic increase and have reached epidemic proportions, even in developing countries. Diabetes, cardiovascular disease, and cancer are the most frequent NCDs and the underlying risk factors including Insulin resistance, dyslipidemia and obesity have been increasing over the last decades. The current study explores the prevalence of advanced fibrosis in an HIV-infected outpatient study population.

Enrollment: 300 estimated patients

Sex: All

Ages: 18+ years old

Volunteers: Accepts Healthy Volunteers

Inclusion criteria

• informed consent
• age >18

Exclusion criteria

• pregnancy
• disease with expectation of life under 12 months