Prevalence of Amyloidosis in Trauma Patients (APTUR)

Consorci Sanitari de l'Alt Penedès i Garraf

Status: Enrolling

Conditions: Amyloidosis

Treatments: Procedure: Traumatologic surgery

Study type: Observational

Funder types: Other

Identifiers

NCT06527521

CSAPG-61

Details and patient eligibility

About

This study aims to determine the frequency of amyloidosis among patients undergoing trauma surgery.

Enrollment: 246 estimated patients

Sex: All

Volunteers: No Healthy Volunteers

Inclusion criteria

• Men and women included in the waiting list for scheduled trauma surgery with at least one of the following criteria defined as red flags: Over 65 years old; Possible family history of amyloidosis, Cardiac pathology: aortic stenosis, presence of left ventricular hypertrophy defined as interventricular septal thickness > 12mm measured by echocardiography, history of previous brady- or tachyarrhythmias including cardiac conduction blocks, history of syncope or presyncope, pro BNP > 300 in previous blood tests; History of sensory peripheral neuropathy; History of nephropathy without etiological diagnosis; History of liver disease without a clear cause.
• Ability to cooperate in the necessary evaluations.
• Signed informed consent for inclusion in the study, either by the participant or their legal representative.

Exclusion criteria

- Participants previously diagnosed with amyloidosis cannot be included in the study.