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Prevalence of and Factors Associated With Metabolic Syndrome in Schizophrenia

C

Chiang Mai University

Status

Completed

Conditions

Quality of Life
Depression
Metabolic Syndrome

Study type

Observational

Funder types

Other

Identifiers

NCT01587521
PSY-11-07-26A-12

Details and patient eligibility

About

Patients with schizophrenia are more likely to have metabolic syndrome compared to general population. The criterion for metabolic syndrome in Asian people including: elevated waist circumference (male ≥ 90cm, female ≥ 80cm), elevated triglycerides ≥ 150mg/dL, reduced HDL cholesterol: male < 40mg/dL, female < 50mg/dL, elevated blood pressure: ≥ 130/85 mmHg, elevated fasting glucose: ≥ 100mg/dL. Several factors have been found to be associated with metabolic syndrome in schizophrenia, e.g. age, antipsychotic drugs, smoking, family history of metabolic disorder, stress, and quality of life.

However, little is known about the prevalence of and factors associated in Asian. This study aimed to:

  1. Identify the prevalence of metabolic syndrome in patients with schizophrenia.
  2. Identify the factors associated with metabolic syndrome in patients with schizophrenia.

Full description

Patients with schizophrenia are more likely to have metabolic syndrome compared to general population. The criterion for metabolic syndrome in Asian people including: elevated waist circumference (male ≥ 90cm, female ≥ 80cm), elevated triglycerides ≥ 150mg/dL, reduced HDL cholesterol: male < 40mg/dL, female < 50mg/dL, elevated blood pressure: ≥ 130/85 mmHg, elevated fasting glucose: ≥ 100mg/dL. Several factors have been found to be associated with metabolic syndrome in schizophrenia, e.g. age, antipsychotic drugs, smoking, family history of metabolic disorder, stress, and quality of life.

However, little is known about the prevalence of and factors associated in Asian. This study aimed to:

  1. Identify the prevalence of metabolic syndrome in patients with schizophrenia.
  2. Identify the factors associated with metabolic syndrome in patients with schizophrenia.

Method This study is a cross-sectional study conducting at the Faculty of Medicine, Chiang Mai University. Eighty participants will be recruited with the inclusion criteria of having diagnosed with schizophrenia according to DSM-IV-TR and aged 18 years or over. The exclusion criterion is having organic brain syndrome.

Measurements PANSS CDSS WHOQOL-BREF-THAI

Enrollment

80 patients

Sex

All

Ages

18 to 100 years old

Volunteers

No Healthy Volunteers

Inclusion criteria

  • Diagnosis of schizophrenia according to DSM-IV-TR
  • Aged 18 years-old or over

Exclusion criteria

  • Having organic brain syndromes

Trial contacts and locations

1

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Data sourced from clinicaltrials.gov

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