Prevalence of Antiphospholipid Antibodies Among Women With Preeclampsia

Mohamed Sayed Abdelhafez

Status: Completed

Conditions: Preeclampsia

Treatments: Other: Testing for antiphospholipid antibodies

Study type: Observational

Funder types: Other

Identifiers

NCT02699437

HME

Details and patient eligibility

About

The purpose of this study is to determine the prevalence of positive antiphospholipid antibodies among women with preeclampsia and to determine the effect of antiphospholipid antibodies on the severity of preeclampsia and the obstetric outcomes

Full description

For all women included in the study, blood samples will be tested for anticardiolipin antibodies and lupus anticoagulant. The clinical details of all women will be collected by reviewing their hospital and prenatal records. The following clinical characteristics will be evaluated: maternal age, previous gestations, parity, past or family history of preeclampsia, gestational age at the onset of preeclampsia, gestational age at delivery and birth weight. The following pregnancy and delivery complications will be assessed: placental insufficiency, intrauterine growth restriction, fetal loss (stillbirth) and early neonatal death.

Enrollment: 200 patients

Sex: Female

Ages: 20 to 35 years old

Volunteers: No Healthy Volunteers

Inclusion criteria

• Pregnant women with preeclampsia.

Exclusion criteria

• Women with systemic autoimmune disease.
• Women with active thromboembolic disorders.
• Women with history of previous thromboembolic disorders.

Trial design

200 participants in 1 patient group

Pregnant women with preeclampsia

Description:

Testing for antiphospholipid antibodies (anticardiolipin antibodies and lupus anticoagulant) will be performed in pregnant women with preeclampsia.

Treatment:

Other: Testing for antiphospholipid antibodies