Prevalence of Bacteria Following Endodontic Treatment

King's College London

Status: Unknown

Conditions: Root Canal Infection

Treatments: Diagnostic Test: Detection of residual vital bacteria in the root canal space

Study type: Observational

Funder types: Other

Identifiers

NCT03055975

05/Q0705/051

Details and patient eligibility

About

Sampling of accessed root canals with endodontic paper points during treatment and immediately pre-obturation of endodontic root canals was carried out.

Full description

Following ethical approval (REC ref: 05/Q0705/051), informed consent was obtained from patients undergoing root canal treatment.The teeth included in the study had been referred to a specialist centre for the treatment of endodontic infection. They all responded negatively to vitality tests and presented pre-operative apical radiolucencies. The source population were referred by their general dental practitioner into specialist endodontic clinics of Guy's Hospital, King's College London Dental Institute.Treatments on the teeth were carried out by a total of 19 postgraduate endodontic students.

Enrollment: 200 estimated patients

Sex: All

Ages: 18 to 65 years old

Volunteers: No Healthy Volunteers

Inclusion criteria

• Patients with single or multi-rooted teeth undergoing root canal treatment.

Exclusion criteria

• For certain aspects of the study secondary treatments and vital teeth are excluded.

Trial design

200 participants in 2 patient groups

Primary treatments

Description:

Patients undergoing primary root canal treatments. Only teeth which have not previously been accessed are included in this cohort.The source population are adults aged 18-65, referred by their general dental practitioner into specialist endodontic clinics of Guy's Hospital

Treatment:

Diagnostic Test: Detection of residual vital bacteria in the root canal space

Re-treatments

Description:

Patients undergoing re-treatments. Only teeth which had a previous root canal treatment which failed are included in this cohort.The source population are adults aged 18-65, referred by their general dental practitioner into specialist endodontic clinics of Guy's Hospital

Treatment:

Diagnostic Test: Detection of residual vital bacteria in the root canal space