Prevalence of Carbohydrate Intolerance in Lean and Obese Children

National Center for Research Resources (NCRR)

Status: Unknown

Conditions: Diabetes; Obesity; Glucose Intolerance; Acanthosis Nigricans

Study type: Observational

Funder types: NIH

Identifiers

NCT00000112

NCRR-M01RR06022-0029

M01RR006022 (U.S. NIH Grant/Contract)

Details and patient eligibility

About

The prevalence of obesity in children is reaching epidemic proportions. Excess adiposity is more than just a cosmetic problem, having substantial metabolic consequences. Insulin resistance, hyperinsulinemia, impaired glucose tolerance, and frank diabetes are often seen in obese children. In this study the prevalence of impaired glucose (carbohydrate) tolerance in lean children with a family history of diabetes and obese children with acanthosis nigricans with or without a family history of diabetes mellitus will be studied.

Sex: All

Ages: 8 to 18 years old

Volunteers: Accepts Healthy Volunteers

Inclusion and exclusion criteria

Inclusion Criteria:

• Obesity: BM +/- 95% for age general good health