Prevalence of Dissociative Identity Disorder in At-risk Outpatient Groups Reporting Childhood Trauma. (IDENTITY)

Centre Psychothérapique de Nancy

Status: Enrolling

Conditions: Dissociative Disorder

Treatments: Diagnostic Test: semi-structured clinical interview; Diagnostic Test: psychometric assessment

Study type: Interventional

Funder types: Other

Identifiers

NCT06330467

RIPH 2023-02 (Registry Identifier)

2023-A02442-43

Details and patient eligibility

About

The investigators will study the prevalence of dissociative identity disorder (DID) in three populations at risk in cases of childhood psychotrauma : patients with a diagnosis of borderline personality, patients with a diagnosis of functional dissociative crises (FDC) and patients with early psychosis.

The investigators will also study the prevalence of other dissociative disorders and the frequency of complex post-traumatic stress disorder.

The investigators will also look for correlations between the type of maltreatment in childhood, the age of onset of trauma and the type of diagnosis of dissociative disorders.

The investigators hope to include 150 borderline patients, 150 FDC patients and 50 early psychosis patients.

Data collection will be done via a psychometric administration of 7 self-completion questionnaires as well as the completion of the SCID-D semi-structured interview.

Enrollment: 350 estimated patients

Sex: All

Ages: 18+ years old

Volunteers: No Healthy Volunteers

Inclusion and exclusion criteria

I - Inclusion Criteria:

I-1: For all groups:

• Male or female
• Age > or = 18
• Enrolled in or benefiting from a social security scheme
• Patient fluent in French
• Patient willing to undergo a psychological evaluation between 1h30 and 3h30
• Patient with a known history of psychotrauma in childhood before the age of 18 (sexual abuse, mistreatment, school harassment, natural disasters, attacks, etc.).
• Patient having received and understood complete information on the organization of the research and having given written free and informed consent prior to participation in the study.

I-2 : Patients in the borderline group

• Patients with main diagnosis of emotionally labile personality
• Patients with at least one psychiatric hospitalization in the last 3 years

I-3 : Patients in the early psychosis group

Patient with a diagnosis of mental state at risk of psychosis according to the criteria defined by CAARMS (Comprehensive Assessment of At Risk Mental State) OR Patients diagnosed with a first psychotic episode on an outpatient basis or following a hospital stay

I-4 : Patients in the functional dissociative crises group

Patients diagnosed with functional dissociative crises by a specialized epileptologist

II- Non-inclusion criteria

• Impairment of the subject making it difficult or not impossible to participate in the trial or to understand the information provided to him/her
• Patients with specific difficulties in understanding SCID-D questions
• Psychiatric condition requiring hospitalization
• Patients with symptoms of recent toxic consumption (alcohol, cannabis, other ...) disrupting assessment responses
• Patient taking part in a pharmacological study involving a pro-dissociative molecule of the psychedelic type
• Pregnant, parturient or nursing mothers
• Person deprived of liberty by judicial or administrative decision
• Person in a life-threatening emergency
• An adult under legal protection (guardianship, curatorship, safeguard of justice)
• Person unable to give consent and not subject to a legal protection measure

Trial design

Primary purpose: Diagnostic

Allocation: Non-Randomized

Interventional model: Parallel Assignment

Masking: None (Open label)

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350 participants in 3 patient groups

Borderline

Other group

Description:

Borderline patients

Treatment:

Diagnostic Test: psychometric assessment

Diagnostic Test: semi-structured clinical interview

Functional Dissociative Crises (FDC)

Other group

Description:

FDC patients

Treatment:

Diagnostic Test: psychometric assessment

Diagnostic Test: semi-structured clinical interview

Early psychosis

Other group

Description:

Early psychosis patients : mental state at risk for psychosis and first psychotic episode

Treatment:

Diagnostic Test: psychometric assessment

Diagnostic Test: semi-structured clinical interview