Prevalence of HIV +ve Cases With AIDS Defining Opportunistic Infections Among ART Naive Patients Attending ART Centre (ADC)

Singh, Ranjan Kumar, M.D.

Status: Completed

Conditions: Candidiasis, Esophageal; Tuberculosis; Cryptococcosis; Toxoplasmosis; HIV Infections; Leishmaniasis

Treatments: Other: CD4 cell count

Study type: Observational

Identifiers

NCT03993093

SinghRK1

Details and patient eligibility

About

HIV patients are likely to suffer from opportunistic infections, in absence of highly active retroviral therapy. This happens due to lack of awareness of HIV status among patients or unresponsive to anti retroviral drugs. This study is for the prevalence of AIDS defining OIs among treatment naive HIV patients.

Full description

Oppotunistic infections (OIs) happen in persons with weakened immune system. HIV patients, who remain untreated due to lack of knowledge of existing HIV infections, often get OIs. HIV patients with AIDS defining OIs fall into stage 3 of HIV illness. Prevalence of OIs in resource poor settings are tuberculosis (pulmonary and extra pulmonary), toxoplasmosis, cryptococcosis, and oesophageal candidiasis. There are a few data to show AIDS defining OIs in treatment naïve HIV patients. Incidence of OIs among HIV patients in United States, and Canada between 2000 to 2019 was 9%. Leading OIs were peumocystis Jiroveci, oesophageal candidiasis and disseminated MAC or M. kansassi.

Minimal diagnoses at poor settings can be made by observation of symptoms, use of microscope, imaging and diagnostic therapy.

Enrollment: 257 patients

Sex: All

Ages: 5+ years old

Volunteers: No Healthy Volunteers

Inclusion criteria

• HAART naïve HIV patient

Exclusion criteria

• Patients died during screening
• Transferred in HIV patients

Trial design

257 participants in 1 patient group

HIV with OIs

Description:

Treatment naive HIV patients with OIs

Treatment:

Other: CD4 cell count