Prevalence of H.Pylori in Patients With Acne Vulgaris Acne Vulgaris

Sohag University

Status

Completed

Conditions

Helicobacter Pylori Infection

Acne Vulgaris

Treatments

Other: Blood and stool samples collection

Study type

Observational

Funder types

Other

Identifiers

NCT03411733

HPAV001

Details and patient eligibility

About

The objective of the study is to investigate prevalence of H.Pylori infection among acne vulgaris patients.

Full description

The study included patients with acne vulgaris and healthy control participants. The study recruited both sexes, all grades of acne, adolescents and young adults.

All patients were subjected to complete history, general and skin examination Acne vlugaris Patients were classified into mild, moderate and severe according to the classification of American Academy of dermatology for acne vulgaris.

Detection of H. pylori infection:

Blood and stool samples were taken from each participant and was directly transferred to laboratory for detection of H. Pylori antigen and antibody.

An enzyme-linked immune sorbent assay (ELISA) was used for quantitative assessment of IgG antibodies against H.Pylori in human serum.

A monoclonal antibodies based enzyme-linked immunosorbent assay was used to detect H.Pylori specific antigen in stool samples.

Enrollment

90 patients

Sex

All

Ages

12 to 60 years old

Volunteers

Accepts Healthy Volunteers

Inclusion criteria

Acne vulgaris patients
Healthy volunteers (control)

Exclusion criteria

Patients with a history of drug intake that affects H. Pylori such as proton-pump inhibitors, clarithromycin, tetracyclines, amoxicillin or metronidazole within previous two weeks were excluded.