Prevalence Of Hyperhomocysteinemia In Thai Chronic Kidney Disease (CKD) Patients

Bangkok Metropolitan Administration Medical College and Vajira Hospital

Status: Completed

Conditions: Hyperhomocysteinemia; Cardiovascular Disease

Study type: Observational

Funder types: Other

Identifiers

NCT01391416

VJR-0002

Details and patient eligibility

About

It is well recognized that patients with chronic kidney disease (CKD) have an increased risk for cardiovascular disease (CVD) and hyperhomocysteinemia appears to be a predictor of future CVD events. Hyperhomocysteinemia has been reported to bo of high prevalence in patients with CKD. The investigators aim to study the prevalence of hyperhomocysteinemia in Thai CKD patients by using Thai Screening and Early Evaluation of Kidney Disease (SEEK) study database and their relationship to CVD.

Full description

Ninety eight subjects were sampling from Thai SEEK study database Traditional Traditional risk factors of CVD such as total cholesterol, triglyceride, age, sex, history of smoking and blood pressure levels were examined and recorded. Stored sera of these subjects were analyzed for the total homocysteine (tHcy) level. Analysis of variance was used to evaluate the different of mean tHcy among groups

Enrollment: 98 patients

Sex: All

Ages: 18 to 75 years old

Volunteers: Accepts Healthy Volunteers

Inclusion criteria

• CKD stages 3-4 from Thai SEEK Study

Exclusion criteria

• CKD stage 5

Trial design

98 participants in 2 patient groups

CKD stage 3-4

Description:

CKD stage 3-4 from Thai SEEK study

hyperhomocysteine group

Description:

CKD stage 3-4 from Thai SEEK study