Prevalence of Hypogonadism in Male Cancer Patients

Baylor College of Medicine

Status: Completed

Conditions: Cancer; Hypogonadism

Study type: Observational

Funder types: Other; Other U.S. Federal agency; Industry

Identifiers

NCT00472940

H-19709

Details and patient eligibility

About

Cancer and its complications are common problems. In most cases, this condition has a profound impact on survival and quality of life (QoL). Fatigue, sexual dysfunction, decreased sexual drive, depression and poor appetite are commonly seen in these patients. However, these symptoms also are seen in men with other conditions including those with low testosterone levels.

The objective of this study is to determine the number of male patients with cancer that have low testosterone levels and to establish the relationship between testosterone levels and the symptoms that these patients experience.

Enrollment: 135 patients

Sex: Male

Ages: 18+ years old

Volunteers: Accepts Healthy Volunteers

Inclusion criteria

1. Male subjects ≥ 18 years of age with histological diagnosis of cancer for cancer group.
2. Provide written informed consent prior to screening.
3. Histological diagnosis of cancer other than non-melanoma skin cancer for the two cancer groups.

Exclusion criteria

1. Concomitant use of GH, Megestrol, Marinol, or any other anabolic agent, appetite stimulant (including corticosteroids other than dexamethasone at the time of IV chemotherapy administrations), tube feedings, or parenteral nutrition during the 3 months prior to entering the study.
2. Participation in a clinical trial with investigational agents within 1 month of enrollment.
3. Prior or current use of other medications that interfere with gonadal axis (androgens, estrogens, anti-androgens, etc).