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Prevalence of May-Thurner Syndrome in 1st-degree Relatives of Symptomatic Patients (MTS)

U

University Hospital of Limerick

Status

Begins enrollment in 1 month

Conditions

May-Thurner Syndrome

Treatments

Other: No Intervention

Study type

Observational

Funder types

Other

Identifiers

Details and patient eligibility

About

The aim is to assess the prevalence of May-Thurner syndrome in 1st-degree relatives of previously identified symptomatic patients.

Full description

May-Thurner syndrome (MTS) is a condition characterised by compression of the left common iliac vein by the right common iliac artery and the anterior spine of the 5th lumbar vertebrae. Previously thought to be a rare condition, the prevalence of MTS is thought to be underreported. MTS can lead to significant morbidity in the form of chronic venous insufficiency, venous ulceration, lower limb swelling, venous claudication, deep-vein thrombosis, varicose veins, pelvic congestion syndrome, chronic pelvic pain and chronic post-thrombotic syndrome. It is a known risk factor for development of venous incompetence and varicose veins in adolescents and young adults. Furthermore, it is known to be an a causative factor in the development of "unprovoked" DVT in younger patients, however data on the risk of development of DVT in MTS patients has to date, been unavailable.

The pathogenesis of MTS is largely unknown and whilst the condition is known to be more prevalent in females, familial risk factors are largely unknown. To date, no studies have previously assessed the prevalence of MTS in relatives of those with the condition.

Enrollment

50 estimated patients

Sex

All

Ages

18+ years old

Volunteers

No Healthy Volunteers

Inclusion criteria

  • Informed consent, first degree relative with symptomatic May-Thurner syndrome

Exclusion criteria

  • Those who not give informed consent to be contacted or to be scanned.

Trial contacts and locations

0

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Central trial contact

Fiona Leahy, MSc

Data sourced from clinicaltrials.gov

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