Prevalence of Molar Incisor Hypomineralization Among Children Treated With Asthmatic Drugs Early in Their Lives

Cairo University (CU)

Status: Completed

Conditions: Asthma in Children; Molar Incisor Hypomineralization

Study type: Observational

Funder types: Other

Identifiers

NCT04103710

MIH and asthmatic children

Details and patient eligibility

About

The aim of this study is to assess the prevalence of molar incisor hypo mineralization among children who have been treated with asthmatic drugs during the first three years of life.

Full description

The term Molar incisor hypo mineralization (MIH) was first introduced in 2001 as a developmental disorder of enamel characterized by hypo mineralization -of systemic origin - affecting the enamel of first permanent molars (PFM) ,frequently associated with affected permanent incisors.

The prevalence of MIH varies widely, ranging from 2.4 % to 40.2% in different populations. This wide variation may be due to differences in diagnostic criteria and methodologies used by the authors. Concerning the etiology of MIH it is mostly related to pre natal, perinatal, and post natal illness.

Asthma and asthmatic drugs have been proposed to be one of the etiological factors of MIH,Internationally, the mean prevalence of pediatric asthma is 10%.

Enrollment: 167 patients

Sex: All

Ages: 8 to 12 years old

Volunteers: No Healthy Volunteers

Inclusion criteria

1. Children from 8 to 12 years old with fully erupted first permanent molars and permanent incisors.
2. Children who were patients of the Pediatric Pulmonary Clinic and had used asthma drugs (oral and inhaled bronchodilators or corticosteroids) during their first three years of life.

Exclusion criteria

1. Children with any chronic disease
2. Children with unerupted or partially erupted first permanent molars.
3. Children using a fixed orthodontic appliance
4. Children having extensive carious lesions that might mask dental enamel defects.