Prevalence of MTHFR Polymorphisms in Venous Disease

Health Diagnostic Laboratory

Status: Completed

Conditions: MTHFR; Thrombosis; Venous Disease; Varicose Veins

Study type: Observational

Funder types: Industry

Identifiers

NCT01993914

R2011-2104

Details and patient eligibility

About

The etiologies of varicose veins and the progression to more serious forms of chronic venous disease and identification of appropriate diagnostic tests to better aid patient management by identifying individuals who may benefit from more aggressive treatment and/ or prophylactic measures.

Enrollment: 90 patients

Sex: All

Ages: 18+ years old

Volunteers: Accepts Healthy Volunteers

Inclusion criteria

• Age 18 or over
• No venous disease (N=30); or C2-C3 venous disease (N=30); or C4-C6 venous disease (N=30)

Exclusion criteria

• Pregnancy

• Cancer

• Chronic obstructive pulmonary disease (COPD)

• Any systemic inflammatory disease

• Any of the following within the previous 30 days:

  • Trauma
  • Any surgery
  • Periods of prolonged inactivity