PRevalence of Obstructive Sleep apnoEa and Reduction of Promoters in AF (PROSERPin-AF)

Istituto Auxologico Italiano

Status: Active, not recruiting

Conditions: Atrial Fibrillation; Osa Syndrome

Treatments: Diagnostic Test: Polysomnography; Behavioral: Lifestyle counselling

Study type: Observational

Funder types: Other

Identifiers

NCT05784077

09C020

Details and patient eligibility

About

This study aims to identify how many patients who have atrial fibrillation, also have sleep apnoea. This is important because sleep apnoea can be a trigger to atrial fibrillation and it can be corrected with a simple intervention. Therefore it is important to understand its prevalence (how many patients with atrial fibrillation are affected by it). Also, obesity and sleep disorders are often associated, therefore the evolution of atrial fibrillation is studied in patients who also have obesity and have lost weight compared with patients who did not loose any weight or are not obese. As medications or therapy are not changed, this is an observational study.

Enrollment: 343 estimated patients

Sex: All

Ages: 18 to 75 years old

Volunteers: No Healthy Volunteers

Inclusion and exclusion criteria

Inclusion Criteria primary outcome:

• 1 episode of atrial fibrillation in the previous year

Inclusion Criteria secondary outcome:

• BMI > o = 27Kg/m2
• AHI >30 o con 15<AHI<30 associated with other symptoms (sleeplessness, uncontrolled hypertension and cerebral events)

Exclusion Criteria:

• Ejection Fraction <50%
• HFpEF not related to atrial fibrillation.
• coronary artery disease
• valvular cardiomyopathy
• patient already in treatment for sleep apnoea
• hyperthyroidism