Prevalence of Periodontitis in Egyptian Multiple Sclerosis Patients.

Cairo University (CU)

Status: Not yet enrolling

Conditions: Periodontal Diseases; Multiple Sclerosis (MS)

Study type: Observational

Funder types: Other

Identifiers

NCT07195110

PER4-1-2

Details and patient eligibility

About

The goal of this observational study is to explore the association between multiple sclerosis and periodontal disease in a sample of Egyptian population

The main question it aims to answer is:

• Is there an association between MS and periodontal disease Participants already diagnosed with multiple sclerosis. A conventional oral examination will be held on a dental unit, filling charts and patients' acceptance to participate in the survey.

Full description

Periodontal disease is a chronic inflammatory condition leading to progressive destruction of the supporting structures of the teeth. Multiple sclerosis (MS) is a chronic autoimmune disease of the central nervous system that may share common inflammatory pathways with periodontal disease. Recent evidence suggests that systemic inflammation may influence the severity and progression of both conditions.

This study will recruit participants already diagnosed with MS and assess their periodontal status using standard clinical parameters, including clinical attachment loss (CAL), probing pocket depth, and bleeding on probing measured at six sites per tooth using a periodontal probe. Data will be collected through a conventional oral examination in a dental unit, and results will be compared to evaluate the prevalence and potential association between MS and periodontal disease within this population.

Enrollment: 293 estimated patients

Sex: All

Ages: 18+ years old

Volunteers: No Healthy Volunteers

Inclusion criteria

• Patients diagnosed with MS
• Adult patients ≥ 18 years old.
• Patients providing an informed consent

Exclusion criteria

• Periodontal therapy within the last 3 months.
• Having surgical therapy or undergoing orthodontic treatment
• Smokers
• Pregnant females
• Patients with systemic condition know to impact the periodontal condition other than MS (eg. Diabetes Mellitus)
• Patients having more than 5 lost teeth