Prevalence of Preoperative Dehydration in Major Elective Urologic Surgery and Its Impact on Postoperative Outcome (DEHYD)

Insel Gruppe AG, University Hospital Bern

Status: Terminated

Conditions: Postoperative Complications; Dehydration; Postoperative Nausea and Vomiting

Study type: Observational

Funder types: Other

Identifiers

NCT03788070

LOLD 01-19

Details and patient eligibility

About

The primary objective of this study is to measure the prevalence of preoperative dehydration in elective major abdominal urologic surgery when we apply our daily standard operation procedures. Secondary objectives are to assess the impact of preoperative dehydration on postoperative outcome. The hypothesis is that preoperative dehydration leads to more postoperative complications.

Full description

The information about the impact of preoperative dehydration on postoperative outcome is conflicting. One of the reported difficulties of the studies in this field is to get adequate power for statistical significance. The incidence of preoperative dehydration in different surgical populations has been reported in about one third of patients. The prevalence in the urologic population is not known.

This is a monocentric observational study with no study intervention. The goal is to consecutively include all patients undergoing major urologic surgery during 365 days who meet the inclusion criteria to assess the prevalence of preoperative dehydration in elective major abdominal urologic surgery when the standard operation procedures of the University Hospital Bern are applied.

Enrollment: 188 patients

Sex: All

Ages: 18+ years old

Volunteers: No Healthy Volunteers

Inclusion criteria

• >18 years old
• Major elective urologic surgery i. Prostate surgery ii. Bladder surgery iii. Kidney surgery iv. Various laparotomies / laparoscopies (e.g. retroperitoneal lymphadenectomy)
• Standard procedure planned
• Standard perioperative management planned
• Informed consent

Exclusion criteria

• Preoperative iv-fluids
• Pregnancy (which is a contraindication to this type of surgery per se)
• Inability to give informed consent (e.g. severe psychiatric disorder, dementia)
• Inability to complete the Quality of Recovery (QoR) questionnaire
• Enrolment of the investigator, his/her family members, employees and other dependent persons