Prevalence of SARS-CoV-2 Genome in Tears of Asymptomatic and Moderately Symptomatic COVID-19 Patients (COVIDEYE)

Assistance Publique - Hôpitaux de Paris

Status: Terminated

Conditions: SARS-CoV-2

Treatments: Diagnostic Test: conjunctival swab

Study type: Interventional

Funder types: Other

Identifiers

NCT04654325

2020-A02996-33 (Other Identifier)

APHP201268

Details and patient eligibility

About

To evaluate the prevalence of SARS-CoV-2 genome in patients with asymptomatic and moderately symptomatic COVID19.

Full description

Patients attending to the COVID19 screening facility of Paris South University hospital and willing to participate to the study will have both nasopharyngeal and conjunctival swab for SARS-CV-2 genome detection using PCR. The project will evaluate the prevalence of positive conjunctival swabs in patients with positive nasopharyngeal swab. These results will be corelated to symptoms of disease assessed with a standardized questionnaire.

Enrollment: 534 patients

Sex: All

Ages: 18+ years old

Volunteers: No Healthy Volunteers

Inclusion criteria

• Patients receiving diagnostic nasopharyngeal PCR for COVID-19 as part of the usual care
• Age ≥ 18.
• Information and signature of consent
• Affiliated with a social security scheme or entitled

Exclusion criteria

• Refusal to participate in the study
• Eye surgery less than 3 months old
• Unable to give informed consent
• No coverage through the health insurance system
• Patient under judicial protection
• Patient on AME

Trial design

Primary purpose: Other

Allocation: N/A

Interventional model: Single Group Assignment

Masking: None (Open label)

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534 participants in 1 patient group

Patients attending to the COVID19 screening facility

Other group

Description:

Patients will have both nasopharyngeal and conjunctival swab for SARS-CV-2 genome detection using PCR. Study will evaluate the prevalence of positive conjunctival swabs in patients with positive nasopharyngeal swab. These results will be corelated to symptoms of disease assessed with a stan

Treatment:

Diagnostic Test: conjunctival swab