Prevalence of Toxoplasma Gondii and Toxocara Canis Among Patients With Uveitis

National Institute of Health, Korea

Status: Completed

Conditions: Uveitis

Study type: Observational

Funder types: Other

Identifiers

NCT01837056

Nuneuveitis

Details and patient eligibility

About

Investigate the prevalence of Toxoplasma gondii and Toxocara canis in Uveitis

• serum antibody to T. gondii and T. canis
• PCR with peripheral blood for T. gondii and T. canis
• PCR with aqueous humor for T. gondii and T. canis
• Clinical manifestation of patient with uveitis

Full description

Consecutive patients with uveitis are enrolled in Nune Eye Hospital.

Serum ELISA

• IgM,IgG antibody to Toxoplasma gondii
• IgG antibody to Toxocara canis

PCR

• PCR with serum and aqueous humor to Toxoplasma gondii
• PCR with serum and aqueous humor to Toxocara canis Clinical characteristics
• visual acuity
• intraocular pressure (IOP)
• location and degree of inflammation
• other fundus findings were recorded

questionnaire

• environment, occupation
• pet ownership, exposure to animal
• history of eating raw liver of animal, raw beef or any other raw flesh of animal.

Enrollment: 98 patients

Sex: All

Volunteers: No Healthy Volunteers

Inclusion criteria

• patients with uveitis

Exclusion criteria

• Patients with history of major ophthalmic surgery within 6 months
• antiviral, antifungal or antiparasitic therapy within 6 months