Prevalence Rate, and Clinical Characteristics of Obesity Hypoventilation Syndrome Via Screening Patients Admitted to Medical Intensive Care Units

National Taiwan University

Status: Completed

Conditions: Obesity Hypoventilation Syndrome

Study type: Observational

Funder types: Other

Identifiers

NCT02934581

201409020RINC

Details and patient eligibility

About

A prospective observation study to screen adult obese (BMI ≥30 kg/m2) patients who were newly admitted to the medical intensive care units and turned out to be diagnosed as Obesity hypoventilation syndrome(OHS). The investigators purpose is to look into the prevalence, predictive factors, and outcomes of OHS in these critically ill patients.

Enrollment: 52 patients

Sex: All

Ages: 20 to 80 years old

Volunteers: No Healthy Volunteers

Inclusion criteria

• BMI ≥ 30 kg/m2
• Suspected chronic hypercapnia as following Paco2 ≥ 45 mmHg, HCO3- ≥ 27mEq/L or base excess, BE ≥ 2 mEq/L

Exclusion criteria

• Malignancy with lung involvement
• Autoimmune disease with lung involvement
• Moderate to severe obstructive respiratory pattern via spirometry
• Uncontrolled endocrine disease
• Pregnancy
• Pneumonia confirmed by image
• Out-of-hospital cardiac arrest
• Lung edema
• Foreigner of Taiwan