PREventing Pain After Surgery (PREPS)

Mass General Brigham

Status

Enrolling

Conditions

Back Injuries

Disc Herniation

Pain, Back

Spondylolisthesis

Spinal Stenosis

Spondylosis

Treatments

Behavioral: ACT intervention

Study type

Interventional

Funder types

Other

Identifiers

NCT05306665

2022P002302

Details and patient eligibility

About

The present study aims to adapt and modify a brief presurgical Acceptance and Commitment Therapy (ACT) intervention aimed at preventing the transition to Chronic Post-Surgical Pain (CPSP) and reducing long-term opioid use. Investigators will then assess the acceptability, feasibility, and preliminary efficacy of the finalized intervention to prevent the transition to CPSP and reduce post-surgical opioid use six months following lumbar spine surgery. Finally, investigators will identify psychosocial and psychophysical phenotypes associated with response to this intervention.

Enrollment

140 estimated patients

Sex

All

Ages

22+ years old

Volunteers

No Healthy Volunteers

Inclusion criteria

scheduled to undergo fusion, discectomy, vertebroplasty, kyphoplasty, or foraminotomy
age 22 and older
able to communicate fluently in English

Exclusion criteria

inability to complete study procedures due to delirium, dementia, psychosis, or other cognitive impairment
have a history of severe neurologic movement disorder
are pregnant or intent to become pregnant during study
have undergone previous spinal surgery
have spinal deformity, pseudarthrosis, trauma, infection, or tumor as primary indication for surgery
have undergone Acceptance and Commitment Therapy in last 2 years