Preventing Seroma Formation After Stripping Saphenous Vein in Coronary Bypass

Naval Military Medical University

Status: Completed

Conditions: Coronary Bypass Graft Stenosis of Autologous Vein

Treatments: Procedure: vacuum assisted closure; Procedure: Axillary dissection

Study type: Interventional

Funder types: Other

Identifiers

NCT02010996

PSF20131201

Details and patient eligibility

About

The great saphenous vein is the most commonly used material in coronary vascular bridging operation. Coronary bypass operation to obtain the great saphenous vein is mainly through the incision open groin to ankle. This operation may damage the lymphatic, cause lymph circumfluence obstacle, cause fat liquefaction, scar formation, wound dehiscence, around hematoma and other a series of symptoms.Based on some studies and our experience that vacuum assisted closure （VAC）is effective in complex wound failures following Stripping saphenous vein, we use VAC to prevent seroma formation after Stripping saphenous vein in Coronary bypass. This study is aimed to evaluate the efficacy and economics benefits of early VAC application on postoperative complications and wound healing after Stripping saphenous vein in Coronary bypass in comparison to conventional suction drain.

Enrollment: 72 patients

Sex: All

Ages: 10 to 80 years old

Volunteers: No Healthy Volunteers

Inclusion criteria

• Written informed consent
• Coronary heart disease patients to transplant more than 2 vascular bridge
• The thigh groin following from the saphenous vein

Exclusion criteria

• Subjects does not agree to participate in clinical trials
• Subjects had a injury, operation history of Thigh
• Subjects having ever received chemotherapy before the surgery
• Subjects with known hypersensitivity to components of the surgical sticky membrane

Trial design

Primary purpose: Prevention

Allocation: Randomized

Interventional model: Parallel Assignment

Masking: Single Blind

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72 participants in 2 patient groups

Vacuum assisted closure

Experimental group

Description:

Vacuum assisted closure (also called vacuum therapy, vacuum sealing or topical negative pressure therapy) is a sophisticated development of a standard surgical procedure, the use of vacuum assisted drainage to remove blood or serous fluid from a wound or operation site.

Treatment:

Procedure: vacuum assisted closure

Axillary dissection

Active Comparator group

Description:

Axillary dissection is a surgical procedure that incises (opens) the armpit (axilla or axillary) to identify, examine, or remove lymph nodes (small glands, part of the lymphatic system, which filters cellular fluids).

Treatment:

Procedure: Axillary dissection